A study in the Journal of clinical medicine in 2024 looked at nearly 600 older people with dementia and tinnitus taking Ginkgo biloba extract or placebo. It was an advanced statistical analysis of several previous clinical trials, focusing on whether the effect of the extract on tinnitus intensity and emotional symptoms changed according to gender. The results showed that both men and women benefited similarly, with a moderate reduction in tinnitus distress and improvements in anxiety, depression and cognition.
For those living with or caring for someone with dementia and tinnitus, these data suggest that support with Ginkgo biloba extracts may be associated with improved tinnitus management and emotional state, with no significant differences between sexes. For older adults without dementia, the practical message is that the brain and inner ear share pathways of blood supply, inflammation and emotional balance, so taking care of these axes with daily habits is especially important.
Study links Ginkgo biloba, tinnitus and emotional symptoms in older people with dementia
The work was based on three previous clinical trials in elderly patients with mild or moderate dementia and chronic tinnitus. A total of 594 people, just over 400 women and about 170 men, who had received a standardised extract of Ginkgo biloba or placebo for months, were analysed.
The researchers measured tinnitus intensity on a scale of 0 to 10, as well as anxiety, depression and cognitive performance using validated questionnaires. They found that the extract was associated with a significant decrease in tinnitus distress in both sexes, and that part of this effect appeared to be through an improvement in cognition and symptoms of anxiety and depression. The differences between men and women were small and not considered clinically relevant.
In practical terms, we are talking about moderate changes, not disappearance of tinnitus. However, in the context of dementia, where every small advance in mental clarity and well-being counts, these results are valuable and consistent with previous studies on Ginkgo biloba in brain health.
How Ginkgo biloba can influence the brain, inner ear and mood
Chronic tinnitus is associated with alterations in brain networks that regulate attention, emotion and sound perception. In addition, it often coexists with hearing loss, sustained stress and changes in blood flow to the inner ear and brain. In parallel, dementia involves inflammation, oxidative damage and neurotransmitter imbalances that affect memory and mood.
The Ginkgo biloba extract studied in these trials has been described as a modulator of several of these pathways. The scientific literature indicates that it can promote brain microcirculation, support protection against oxidative stress and modulate the signalling of some neurotransmitters involved in attention and emotion. In the context of the study, this combination was associated with a direct reduction in tinnitus distress and also with an indirect improvement by stabilising anxiety, depression and cognitive performance.
From a physiological perspective, it makes sense that the same plant ingredient would be associated with changes in tinnitus, mood and cognition. Inner ear and brain share delicate blood vessels and neural networks that are very sensitive to inflammation and irrigation quality. When vascular function is supported and inflammatory noise is reduced, the nervous system is better able to process sound and emotional stimuli.
Daily habits that support the brain and may alleviate the impact of tinnitus
Beyond any supplementation, the management of tinnitus in older people, with or without cognitive impairment, relies on a foundation of consistent habits. Prolonged exposure to loud noise, smoking, hypertension and chronic stress are associated with increased risk of annoying tinnitus and poorer quality of life.
Taking care of your hearing means limiting loud noise, wearing protection in noisy work or leisure environments and regularly checking your hearing health. At the same time, maintaining stable blood pressure, proper glucose control and regular physical activity helps the microcirculation of the inner ear and brain.
On the emotional level, relaxation techniques, breathing, tinnitus-specific cognitive behavioural therapy and regular sleep routines help to reduce the subjective burden of tinnitus. A diet rich in fruits, vegetables, nuts and oily fish provides antioxidants and fatty acids that are also related to a better vascular and neuronal environment.
How Nutribiolite’s MINFIRE, a mental performance supplement, aligns with this evidence on Ginkgo biloba
The study focuses on a Ginkgo biloba leaf extract in older people with dementia and tinnitus, and shows consistent benefits in tinnitus discomfort, anxiety, depression and cognitive performance. Ginkgo biloba is also a key component in Nutribiolite’s MINFIRE, a dietary supplement formulated for adults who wish to physiologically support their mental performance and everyday psychological well-being.
In MINFIRE, Ginkgo biloba extract is included as a central focus for the support of cognitive function and mental balance. The clinical research cited above reinforces the interest in this ingredient when thinking about circuits connecting memory, attention, brain flow and mood. Although the product is aimed at adults seeking to maintain mental clarity and focus in their daily lives, and not at people with advanced dementia, it shares the same physiological core as the study, the use of leafy Ginkgo biloba to modulate vascular and neural pathways.
MINFIRE’s formulation combines Ginkgo biloba with other selected nutrients to work synergistically on mental energy, resistance to psychological fatigue and emotional stability, always with the logic of supporting processes already present in the body. It is designed for active people, with a high cognitive load or who wish to take care of their brain in the long term through a mix of healthy habits and specific nutritional support.
Nutribiolite MINFIRE combines Ginkgo biloba extract with other nutrients to support mental performance and psychological well-being in active adults.
Integrating a supplement like MINFIRE into a routine that already includes good nutrition, regular movement and stress management offers a coherent pathway for those who want to care for their mental clarity and emotional balance. The role of Ginkgo biloba in the formula connects with the clinical evidence discussed above and positions the product as an additional support, not a substitute for the lifestyle pillars.
What we can take away from this study for daily brain care
The analysis published in the Journal of clinical medicine shows that Ginkgo biloba extract can be associated with moderate improvements in tinnitus, anxiety, depression and cognition in older people with dementia, with no relevant differences between men and women. This reinforces the idea that supporting the microcirculation and neural environment has an impact on both tinnitus perception and emotional well-being.
For everyday life, the core message is to take integrated care of hearing, brain and mood through cardiovascular health habits, stress management and nutrition rich in active plant compounds. Supplements including Ginkgo biloba, such as MINFIRE, fit into this vision as a physiological booster for adults who wish to maintain their mental performance and psychological balance in a context of high cognitive demand.
This content is for information only and is not a substitute for the advice of a healthcare professional.
Frequently asked questions
What did the study on Ginkgo biloba and tinnitus in people with dementia show?
The analysis pooled data from three clinical trials in older people with mild to moderate dementia and tinnitus. Ginkgo biloba extract was associated with a moderate reduction in tinnitus distress and improvements in anxiety, depression and cognition, with no relevant differences between men and women.
Do these results apply to healthy adults with ringing in the ears?
The study was conducted in people with dementia, so its findings apply to this group. In healthy adults, interest in Ginkgo biloba focuses on its relationship with brain irrigation and cognitive function, but the specific effects on tinnitus in this population require more specific research.
What role does Ginkgo biloba play in a supplement such as MINFIRE?
In MINFIRE, Ginkgo biloba extract is used as a central ingredient to support cognitive function and mental well-being. It is integrated into a formula that aims to support mental clarity and resistance to psychological fatigue in adults with high intellectual workloads.
Who MINFIRE can make sense for in your daily routine
MINFIRE is intended for adults who already take care of their diet and physical activity and want additional support for their mental performance. It may be of particular interest to people with intellectually demanding days, who are looking to maintain concentration and mental alertness throughout the day.
If I have tinnitus, is it enough to take a supplement with Ginkgo biloba?
No. Management of tinnitus usually requires a combined approach that includes hearing screening, monitoring of cardiovascular factors, stress management and, in some cases, specific habituation therapies. Ginkgo biloba supplementation may be a physiological support within a broader strategy, not a sole solution.
