MINFIRE is a caffeine-free food supplement with nootropic ingredients, developed to help boost concentration, memory, intellectual performance, promote cognitive functions and protect the brain against oxidative stress. This formula combines the active ingredients of 4 concentrated extracts of medicinal plants, 2 natural sources of neurotransmitters (choline and tyrosine) and Phosphatidylserine, an important constituent of the brain’s gray matter. CAFFEINE-FREE: The European Food Safety Authority (EFSA) recommends not consuming more than 400 mg of caffeine per day. If you are already a coffee lover, if you consume other supplements rich in caffeine during the day, or feel a little uncomfortable with products rich in this substance, then MINFIRE was developed especially for you.
- Bacopa: extract 30: 1 (Bacopa monnieri, minimum 50% of bacacosides)
- Choline L-bitartrate
- Lion’s mane: 10: 1 extract (Hericium erinaceus, min. 30% polysaccharides) – source of beta-glucans, hericenones and erinacines
- Green tea: 100: 1 extract (Camellia sinensis, min. 50% EGCG, caffeine free)
- Ginkgo: 50: 1 extract (Ginko biloba, min. 24% flavonoid glycosides, 6% terpene lactones)
- Phosphatidylserine 20% (from vegetable origin/soy).
SUITABLE FOR VEGANS AND VEGETARIANS.
👉 For those who prefer a caffeinated nootropic, check out ONIT
Description: Formula of MINFIRE
MINFIRE combines a very complete list of active principles, working synergistically and effectively without the action of stimulants such as caffeine. The action of MINFIRE is based on the beneficial properties of its ingredients on the cholinergic system, as well as the neuroprotective and cognitive enhancement activities, widely described in the scientific literature.
The formula of MINFIRE contains:
- 200 mg of concentrated extract of Bacopa monnieri standardized in 50% in bacosides, sources of bacosics and saponins. They have neuroprotective properties and properties to improve cognitive abilities.1-4
- 200 mg of choline L-bitrartate, an efficient source of choline, the precursor of acetylcholine, the main neurotransmitter of the parasympathetic nervous system (or cholinergic system).5
- 150 mg of concentrated extract of Hericium erinaceus, source of beta-D-glucans and the terpenoids hericenone and erinazine, which are noted for their protective properties of the functional integrity of cholinergic neurons.6-7
- 150 mg of L-tyrosine, the amino acid precursor of dopamine, adrenaline and noradrenaline neurotransmitters (substances closely related to mood states)8 and thyroid hormones Thyroxine-T4 and triiodothyronine-T3 (responsible for metabolism regulation).9
- 100 mg of concentrated extract of Camellia sinensis, a source of epigallocatechin-3-gallate (EGCG), which protects neuronal cells from associated damage and suppresses the activity of pro-inflammatory metabolites produced in the body.10-11
- 60 mg of concentrated extract of Ginkgo biloba, source of flavonoid glycosides and terpene lactones. It exerts constrictive and dilating effects on blood vessels, increasing blood flow to the brain and consequently its levels of glucose and ATP, resulting in improved cognitive function and mental health.12
- 50 mg of phosphatidylserine 20% from soy lecithin. Phosphatidylserine is the main class of anionic phospholipids that are particularly important in the plasma membrane of neural tissues, responsible for the flexibility and permeability of the cell membrane, allowing the entry and exit of nutrients.13
- Stough, C., et al., The chronic effects of an extract of Bacopa monniera (Brahmi) on cognitive function in healthy human subjects. Psychopharmacology (Berl), 2001. 156(4): p. 481-4.
- Kongkeaw, C., et al., Meta-analysis of randomized controlled trials on cognitive effects of Bacopa monnieri extract. J Ethnopharmacol, 2014. 151(1): p. 528-35.
- Pase, M.P., et al., The cognitive-enhancing effects of Bacopa monnieri: a systematic review of randomized, controlled human clinical trials. J Altern Complement Med, 2012. 18(7): p. 647-52.
- Stough, C., et al., Examining the cognitive effects of a special extract of Bacopa monniera (CDRI08: Keenmnd): a review of ten years of research at Swinburne University. J Pharm Pharm Sci, 2013. 16(2): p. 254-8.
- Lippelt, D.P., et al., No Acute Effects of Choline Bitartrate Food Supplements on Memory in Healthy, Young, Human Adults. PloS one, 2016. 11(6): p. e0157714-e0157714.
- Zhang, C.C., et al., Chemical constituents from Hericium erinaceus and their ability to stimulate NGF-mediated neurite outgrowth on PC12 cells. Bioorg Med Chem Lett, 2015. 25(22): p. 5078-82.
- Friedman, M., Chemistry, Nutrition, and Health-Promoting Properties of Hericium erinaceus (Lion’s Mane) Mushroom Fruiting Bodies and Mycelia and Their Bioactive Compounds. J Agric Food Chem, 2015. 63(32): p. 7108-23.
- Blanco, A. and G. Blanco, Chapter 16 – Amino Acid Metabolism, in Medical Biochemistry, A. Blanco and G. Blanco, Editors. 2017, Academic Press. p. 367-399.
- Watson, P., Tyrosine supplementation: Can this amino acid boost brain dopamine and improve physical and mental performance? Sports Science Exchange, 2016. 28(157): p. 1-6.
- Higdon, J.V. and B. Frei, Tea Catechins and Polyphenols: Health Effects, Metabolism, and Antioxidant Functions. Critical Reviews in Food Science and Nutrition, 2003. 43(1): p. 89-143.
- Scapagnini, G., et al., Modulation of Nrf2/ARE Pathway by Food Polyphenols: A Nutritional Neuroprotective Strategy for Cognitive and Neurodegenerative Disorders. Molecular Neurobiology, 2011. 44(2): p. 192-201.
- Warburton, D.M. Clinical Psychopharmacology of Ginkgo Biloba Extract. 1988. Berlin, Heidelberg: Springer Berlin Heidelberg.
- Kim, H.-Y., B.X. Huang, and A.A. Spector, Phosphatidylserine in the brain: metabolism and function. Progress in lipid research, 2014. 56: p. 1-18.
|Bacopa herb extract 30:1 (Bacopa monnieri L. Wettst) titrated to 50% in bacosides||200|
|Lion’s mane fruiting body extract 10:1 (Hericium erinaceus Bull. Pers.) titrated to 30% in polysaccharides||150|
|Green tea leaf extract 100:1 (Camellia sinensis L. Kuntze) titrated to 95 % in polyphenols, 80 % in catechins and 50% in EGCG||100|
|Ginkgo leaf extract 50:1 (Ginkgo biloba L) titrated to 24% in flavonoid glycosides and 6% in terpene lactones||60|
|Phosphatidylserine 20% in soy lecithin||50|
*: 2 capsules (recommended daily dose)
Other ingredients: Anti-caking agent (vegetable magnesium stearate); capsule: coating agent (hydroxypropylmethylcellulose), gelling agent (gellan gum).
✅ VEGETAL CAPSULES
✅ NON IRRADIATED
✅ BPA FREE
✅ LACTOSE FREE
✅ SUITABLE FOR VEGANS AND VEGETARIANS
In food supplement reviews, results may vary from person to person. Customer opinions are independent and do not represent the views of Nutribiolite SL.