Why combine iron with folate and vitamin C?

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What are the benefits of combining iron with folate and vitamin C? A protocol published in the *Journal of Ayurveda and Integrative Medicine* (2026) sets out to investigate how to improve oral supplementation with iron and folic acid.

Nutribiolite’s Iron Complex combines iron bisglycinate, vitamin C, folate and vitamins B2, B6 and B12. It combines iron with nutrients that aid its absorption and support normal blood formation, all in a single daily capsule.

Nutribiolite combines iron and folate to support normal blood formation

The article describes a planned randomised, open-label, parallel-group trial in women aged 18 to 49 with mild or moderate iron-deficiency anaemia in India. It will compare ferrous sulphate and folic acid with the same regimen plus Drakshavaleha, an Ayurvedic preparation, over a three-month period. The publication presents the protocol, but no results are yet available. The intervention uses different forms, doses and a different combination of Nutribiolite, so it does not provide evidence of the product’s efficacy either.

The relationship between iron and blood formation helps to explain the choice of these nutrients. Iron contributes to the normal formation of red blood cells and haemoglobin, the protein that carries oxygen in the blood. Folate contributes to normal blood formation and plays a role in cell division.

Each Nutribiolite capsule provides 20 mg of iron and 400 µg of folate. The formula also contains vitamins B6 and B12, which contribute to the normal formation of red blood cells, and vitamin B2, which is involved in normal iron metabolism. It thus combines nutrients with complementary functions in a single dose.

Vitamin C combined with iron to aid its absorption

Iron utilisation is central to the protocol’s approach. Nutribiolite contains vitamin C, which enhances iron absorption. Each capsule provides 80 mg, equivalent to 100 per cent of the reference intake for adults, and also contributes to normal energy metabolism.

The introduction to the article cites a previous open-label equivalence trial in patients with anaemia. It found equivalent results between iron alone and iron plus vitamin C in terms of haemoglobin recovery and absorption. It is therefore important to distinguish between the nutritional function of vitamin C and any additional clinical benefit, which that trial did not demonstrate.

Nutribiolite identifies its sources of nutrients. It uses ferrous bisglycinate, a form in which iron is bound to two molecules of the amino acid glycine, and folate as L-5-MTHF, a metabolically active form of vitamin B9. These designations make it clear what each capsule contains.

A simple guide to maintaining your daily intake

The protocol highlights forgetfulness as a challenge in adhering to a supplementation regime. In day-to-day use, combining the nutrients into a single dose simplifies organisation. The Iron Complex is taken at a rate of one capsule a day with a glass of water. Its 120 capsules provide a 120-day supply, approximately four months.

The formula is suitable for vegans and uses vegetable capsules. Furthermore, it contains no added sugars, colourings or artificial flavourings – characteristics that can be verified by those seeking a formulation compatible with their dietary preferences.

This product is for adults only. Do not exceed the recommended daily dose. Food supplements should not be used as a substitute for a varied and balanced diet and a healthy lifestyle. If fatigue persists, seek medical advice to assess the cause and the need for iron supplementation.

Choosing the Iron Complex allows you to combine iron, vitamin C and folate in a simple regimen, with nutrients that support normal blood formation and help reduce tiredness and fatigue.

Complejo de hierro y vitaminas C, B2, B6, B12 y folato

The Iron Complex combines iron, vitamin C and folate to support normal blood formation. Its 120 vegetarian capsules provide a 120-day supply when taken daily.

Frequently Asked Questions

How much iron does each capsule contain?

Each capsule provides 20 mg of iron from ferrous bisglycinate, a form of iron bound to the amino acid glycine.

Why does it contain vitamin C?

Vitamin C enhances iron absorption and contributes to normal energy metabolism. The formula provides 80 mg per capsule.

What form of folate does it contain?

It contains 400 µg of folate per capsule in the form of calcium L-5-methyltetrahydrofolate, also known as L-5-MTHF.

How should it be taken and how long does the pack last?

The recommended dose is one capsule a day with a glass of water. The pack contains 120 capsules, enough for 120 days.

Is it suitable for a vegan diet?

Yes. Both the ingredients and the capsule are suitable for vegans. Furthermore, the formula contains no added sugars, colourings or artificial flavourings.

This content is for information purposes only and is not a substitute for advice from a healthcare professional.

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