What are the benefits of combining magnesium with vitamins B6 and B12? A trial published in BMC Neurology (2025) investigated a combination of these vitamins in people with carpal tunnel syndrome.
Mag-fusion, from Nutribiolite, combines magnesium, B6, B12, folate and D3 to supplement the diet. The product combines magnesium, which helps to reduce tiredness and fatigue, with specific forms of B vitamins and a daily dose of D3.
Why does Mag-fusion combine magnesium with B6 and B12?
The trial was randomised, double-blind and placebo-controlled. Seventy adults with mild or moderate carpal tunnel syndrome took part at a centre in Malaysia. Over a six-month period, alpha-lipoic acid was evaluated alongside vitamins B1, B6 and B12 (as methylcobalamin), in addition to standard care.
The combination reduced pain, as measured on a visual analogue scale, compared with the placebo, with a statistically significant difference. However, there were no significant differences in nerve conduction, hand function or quality of life. This finding relates to the entire combination studied, which includes alpha-lipoic acid and vitamin B1 – both of which are absent from Mag-fusion – and does not demonstrate that this product relieves pain or treats carpal tunnel syndrome.
In everyday nutrition, magnesium contributes to the normal functioning of the nervous system and to energy metabolism – the processes that enable energy to be obtained and utilised from food. Mag-fusion combines it with vitamins B6 and B12 in a single regimen.
Nutribiolite uses vitamin B6 as pyridoxal-5′-phosphate or P5P, a coenzyme form that assists in metabolic reactions. Vitamin B12 is methylcobalamin, also used in the trial, and folate is included as calcium L-5-methyltetrahydrofolate. The formula thus specifies the specific forms of its three B vitamins.
Mag-fusion combines support for the nervous and muscular systems in a single regimen
Mag-fusion provides 247 mg of elemental magnesium per daily dose, derived from pure magnesium citrate. This is equivalent to approximately 66 per cent of the reference intake for adults. In addition to its role in supporting the nervous system, this mineral contributes to the normal functioning of the muscles.
Vitamin D3 extends this nutritional support by contributing to normal muscle function and the maintenance of bones. Each dose contains 2,000 IU, equivalent to 50 µg, as cholecalciferol. It also contributes to the normal absorption and utilisation of calcium and phosphorus.
The recommended dosage is one capsule twice daily after meals, with water. The pack contains 120 vegetarian capsules and lasts for 60 days, approximately two months. This format allows you to incorporate all five nutrients into your daily routine and plan when to replenish your supply.
Please adhere to the recommended dose. If you are already taking other supplements containing magnesium or vitamin D, check your total intake with a healthcare professional. Supplements should complement, not replace, a varied and balanced diet and a healthy lifestyle.
Mag-fusion combines magnesium for the nervous system and to reduce tiredness, specific forms of B vitamins, and vitamin D3 for muscles and bones. The two-month supply makes it easy to incorporate this combination into your routine.
Mag-fusion combines magnesium for the normal functioning of the nervous system with B6, B12, folate and D3. Its 120 vegetarian capsules provide a 60-day supply.
Frequently asked questions about Mag-fusion
What are the benefits of combining magnesium with B vitamins in Mag-fusion?
It combines magnesium, which contributes to the normal functioning of the nervous system and energy metabolism, with B6, B12 and folate in a single regimen.
What forms of B vitamins does it contain?
It contains B6 as pyridoxal-5′-phosphate (P5P), B12 as methylcobalamin and folate as calcium L-5-methyltetrahydrofolate.
How much magnesium and vitamin D3 does the daily dose provide?
Two capsules provide 247 mg of elemental magnesium from citrate and 2000 IU of D3, equivalent to 50 µg.
How should Mag-fusion be taken?
The recommended dosage is one capsule twice a day after meals, with water. Do not exceed the recommended daily dose of two capsules.
How long does a pack last?
It contains 120 vegetable capsules, enough for 60 days when taken as recommended (two capsules a day).
This information is for guidance only and is not a substitute for advice from a healthcare professional.
