What are the benefits of combining EPA and DHA for cardiovascular health? A meta-analysis published in *Pharmacology Research & Perspectives* (2026) examines this combination in adults with cardiovascular disease and highlights the importance of considering the formulation and dosage.
Nutribiolite’s Omega-3 EPA+DHA with vitamins D3 and K2 combines these two fatty acids from fish oil and both vitamins in a single daily capsule. The product combines support for cardiac, brain and visual function with vitamin D to support bone health and the immune system.
Why Nutribiolite combines EPA and DHA for heart health
The meta-analysis pooled 25 randomised clinical trials involving 25,578 adults with established cardiovascular disease, either in secondary prevention or around the time of heart surgery. Compared with the control groups, no significant reduction in serious cardiovascular events or in atrial fibrillation – a heart rhythm disorder – was observed with the EPA and DHA combinations evaluated.
The authors emphasise that the formulation, dosage and patient characteristics are important when interpreting the results. The analysis did not evaluate the Nutribiolite formulation containing vitamins D3 and K2, and its findings do not support claims that it can prevent heart attacks or arrhythmias.
From a nutritional perspective, EPA and DHA contribute to the normal functioning of the heart. This benefit, recognised in European regulations, is achieved with a daily intake of 250 mg of combined EPA and DHA. Nutribiolite provides 700 mg per capsule, comprising 400 mg of EPA and 300 mg of DHA. The recommended daily intake therefore covers the amount required to achieve this benefit.
Choosing EPA with DHA supports brain and eye health
DHA contributes to the maintenance of normal brain function and vision under normal conditions. Both of these beneficial effects are achieved with 250 mg of DHA per day, an amount covered by the 300 mg contained in a Nutribiolite capsule.
Therefore, when choosing an omega-3 supplement, it is advisable to check the content of each fatty acid, as well as the total amount. The presence of DHA allows these benefits to be combined with the support for heart function provided by its combination with EPA.
Nutribiolite’s fish oil is 80 per cent concentrated in omega-3. Each capsule provides 800 mg of total omega-3, including 700 mg of EPA and DHA. This concentration means the recommended daily intake can be taken in a single capsule, without having to split the dose into several intakes.
Why Nutribiolite adds vitamins to its omega-3 supplement
Vitamin D contributes to the normal absorption and utilisation of calcium and phosphorus, to the maintenance of normal bones, and to the normal functioning of the immune system. These functions are distinct from those of EPA and DHA and enhance the nutritional support provided by the formula.
Nutribiolite provides 2,000 IU of vitamin D3 per capsule, equivalent to 50 µg. It also contains vitamin K2 in the form of menaquinone-7, known as MK-7. Both nutrients are incorporated into the same regimen as the omega-3.
Take one capsule a day with sufficient liquid, preferably with a meal. The capsules are soft, with no fishy smell or taste, and the pack provides a three-month supply. Taking the capsule with a regular meal makes it easier to incorporate into your routine.
A defined intake of EPA and DHA, vitamins in the same capsule and a simple daily routine are the reasons to choose this formula. You can check its features on the product information sheet.
EPA and DHA contribute to normal heart function in a formula containing vitamins D3 and K2. One capsule a day provides a simple regimen for three months’ supplementation.
Frequently Asked Questions
How much EPA and DHA does each capsule contain?
Each capsule provides 400 mg of EPA and 300 mg of DHA, out of a total of 800 mg of omega-3.
Which vitamins are included in the formula?
It contains vitamin D3, at 2,000 IU per capsule, and vitamin K2 in the form of menaquinone-7 or MK-7.
How should it be taken?
Take one capsule a day with plenty of liquid, preferably with a meal. Do not exceed the recommended daily dose.
How long does the pack last?
This pack provides three months’ supply when taken at a rate of one capsule a day.
What precautions should be taken?
It must not be taken by children under 10 years of age or by people being treated with coumarin-based anticoagulants. Vitamin K is also not recommended for those taking other anticoagulants. It contains fish, so it should be avoided if you are allergic to fish. Food supplements should not be used as a substitute for a balanced and varied diet and a healthy lifestyle.
This content is for information purposes only and is not a substitute for advice from a healthcare professional.
